Typical Testing Data/Standard Curve (for reference only)
Rat Microphthalmia-associated transcription factor ELISA Kit | Mitf elisa kit
Rat Microphthalmia-associated transcription factor ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
basic helix-loop-helix-leucine zipper transcription factor; may play a role in osteoclast function [RGD, Feb 2006]
Uniprot Description
MITF: a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Plays a critical role in the differentiation of various cell types including neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. Two isoforms are known: the M-isoform is expressed exclusively in melanocytes, while the A-isoform has a much broader range of expression. Mutations in MITF can lead to Waardenburg syndrome. Ten alternatively spliced isoforms have been described.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Cellular Component: nucleus; protein complex
Molecular Function: chromatin binding; DNA binding; protein dimerization activity; RNA polymerase II transcription factor activity, enhancer binding; transcription factor activity
Biological Process: bone remodeling; camera-type eye development; cell differentiation; cell fate commitment; melanocyte differentiation; multicellular organismal development; negative regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; osteoclast differentiation; pigmentation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein complex assembly; regulation of apoptosis; regulation of cell proliferation; regulation of gene expression; regulation of osteoclast differentiation; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription, DNA-dependent; Wnt receptor signaling pathway
Research Articles on Mitf
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Product Notes
The Rat Mitf mitf (Catalog #AAA2886174) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886174 ELISA Kit recognizes Rat Mitf. It is sometimes possible for the material contained within the vial of "Microphthalmia-associated transcription factor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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