Human Mullerian Inhibiting Substance/Mullerian Hormone ELISA Kit | MIS/AMH elisa kit

Human Mullerian Inhibiting Substance/Mullerian Hormone ELISA Kit

Cat. Num. AAA45898

• Gene Names: AMH; MIF; MIS
• Reactivity: Human
• Synonyms: Mullerian Inhibiting Substance/Mullerian Hormone; Human Mullerian Inhibiting Substance/Mullerian Hormone ELISA Kit; MIS/AMH elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between Human MIS/AMH and analogues was observed.
• Sequence Length: 560

• Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
• Assay Type: Sandwich
• Detection Range: 0.25 ng/ml – 8 ng/ml.
• Sensitivity: 0.1 ng/ml.
• Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate MIS/AMH concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic applications
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for MIS/AMH elisa kit

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate MIS/AMH concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research!

NCBI and Uniprot Product Information

• NCBI GI #: 157266298
• NCBI GeneID: 268
• NCBI Accession #: NP_000470.2
• NCBI GenBank Nucleotide #: NM_000479.3
• UniProt Accession #: P03971; O75246; Q6GTN3
• Molecular Weight: 59,195 Da
• NCBI Official Full Name: muellerian-inhibiting factor
• NCBI Official Synonym Full Names: anti-Mullerian hormone
• NCBI Official Symbol: AMH
• NCBI Official Synonym Symbols: MIF; MIS
• NCBI Protein Information: muellerian-inhibiting factor; anti-Muellerian hormone; Mullerian inhibiting factor; Mullerian inhibiting substance; muellerian-inhibiting substance
• UniProt Protein Name: Muellerian-inhibiting factor
• UniProt Gene Name: AMH
• UniProt Synonym Gene Names: MIF; AMH; MIS
• UniProt Entry Name: MIS_HUMAN

NCBI Description

Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: growth factor activity; hormone activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: sex determination; response to drug; Mullerian duct regression; cell-cell signaling; gonadal mesoderm development; preantral ovarian follicle growth; sex differentiation; response to organic cyclic substance; urogenital system development; activation of NF-kappaB transcription factor; aging

Disease: Persistent Mullerian Duct Syndrome, Types I And Ii