Lens fiber major intrinsic protein (MIP) Recombinant Protein | MIP recombinant protein
Recombinant Dog Lens fiber major intrinsic protein (MIP)
NCBI and Uniprot Product Information
Uniprot Description
Function: Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core
By similarity.
Subunit structure: Homotetramer. Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes
By similarity.
Subcellular location: Membrane; Multi-pass membrane protein
By similarity. Cell junction › gap junction
By similarity.
Domain: Aquaporins contain two tandem repeats each containing two membrane-spanning helices and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Each tandem repeat contains a loop and a short helix that enter and leave the lipid bilayer on the same side
By similarity.
Post-translational modification: Subject to partial proteolytic cleavage in the eye lens core. Partial proteolysis promotes interactions between tetramers from adjoining membranes
By similarity.
Sequence similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]
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Product Notes
The MIP mip (Catalog #AAA1041077) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-263. The amino acid sequence is listed below: MWELRSASFW RAIFAEFFAT LFYVFFGLGA SLRWTPGPLH VLQVALAFGL ALATLVQAVG HISGAHVNPA VTFAFLVGSQ MSLLRAFCYM AAQLLGAVAG AAVLYSVTPP AVRGNLALNT LHPGVSVGQA TTVEIFLTLQ FVLCIFATYD ERRNGRLGSV ALAVGFSLTL GHLFGMYYTG AGMNPARSFA PAILTRNFTN HWVYWVGPII GGGLGSLLYD FLLFPRLKSV SERLSILKGA RPSDSNGQPE GTGEPVELKT QAL. It is sometimes possible for the material contained within the vial of "Lens fiber major intrinsic protein (MIP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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