MIA2 recombinant protein

Recombinant Human MIA2

Gene Names

MIA2; MEA6; MGEA; TALI; MGEA6; CTAGE5; MGEA11

Purity

>95% as determined by SDS-PAGE

Synonyms

MIA2; Recombinant Human MIA2; MIA-2; Recombinant Human Melanoma Inhibitory Activity-2 (MIA2); MIA2 recombinant protein

Ordering
Cat. Num. AAA4159818 For Research Use Only!

Host

E Coli

Purity/Purification

>95% as determined by SDS-PAGE

Form/Format

Lyophilized from a 0.2 um filtered solution in PBS

Sequence Length

654

Endotoxin Level

<1.0 EU/ug of recombinant protein as determined by the LAL method.

Reconstitution

Reconstitute at 100 ug/mL in sterile PBS

Preparation and Storage

The lyophilized protein is stable for at least one year from date of receipt at-70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8 degree C for one month, or at-20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Related Product Information for MIA2 recombinant protein

A small, secreted protein that interacts with extracellular matrix proteins, MIA-2 is expressed predominantly in the liver and weakly in testis. Elevated levels of MIA-2 in patients with severe fibrosis/inflammation/chronic hepatitis presents potential for use as a clinical marker in the identification of hepatic disease activity and severity.

NCBI and Uniprot Product Information

NCBI GI #

46094009

NCBI GeneID

4253

NCBI Accession #

NP_473365.3

NCBI GenBank Nucleotide #

NP_473365.3

UniProt Accession #

Q96PC5

Molecular Weight

11.7 kDa

NCBI Official Full Name

melanoma inhibitory activity protein 2 isoform 9

NCBI Official Synonym Full Names

MIA SH3 domain ER export factor 2

NCBI Official Symbol

MIA2

NCBI Official Synonym Symbols

MEA6; MGEA; TALI; MGEA6; CTAGE5; MGEA11

NCBI Protein Information

melanoma inhibitory activity protein 2

UniProt Protein Name

Melanoma inhibitory activity protein 2

Protein Family

Melanoma inhibitory activity protein

UniProt Gene Name

MIA2

UniProt Entry Name

MIA2_HUMAN

NCBI Description

This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]

Uniprot Description

MIA2: May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. Belongs to the MIA/OTOR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 14q13.2

Cellular Component: extracellular region

Biological Process: cholesterol homeostasis

Research Articles on MIA2

1. TANGO1/CTAGE5 receptor serves as a polyvalent template for assembly of large COPII coats.

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Product Notes

The MIA2 mia2 (Catalog #AAA4159818) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MIA2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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