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Mouse Lipase, Monoacylglycerol ELISA Kit | MGL elisa kit

Mouse Lipase, Monoacylglycerol ELISA Kit

Gene Names
MGLL; MGL; HUK5; MAGL; HU-K5
Reactivity
Mouse
Synonyms
Lipase; Monoacylglycerol; Mouse Lipase; Monoacylglycerol ELISA Kit; MGL elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
283
Assay Type
Quantitative Sandwich
Detection Range
0.625ng/ml-20ng/ml
Sensitivity
0.1ng/ml
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for MGL elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of MGL (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,261 Da
NCBI Official Full Name
monoglyceride lipase isoform 3
NCBI Official Synonym Full Names
monoglyceride lipase
NCBI Official Symbol
MGLL
NCBI Official Synonym Symbols
MGL; HUK5; MAGL; HU-K5
NCBI Protein Information
monoglyceride lipase; monoacylglycerol lipase; lysophospholipase homolog
UniProt Protein Name
Monoglyceride lipase
Protein Family
UniProt Gene Name
MGLL
UniProt Synonym Gene Names
MGL; MAGL
UniProt Entry Name
MGLL_HUMAN

NCBI Description

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Uniprot Description

MGLL: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.

Protein type: Phospholipase; EC 3.1.1.23; Lipid Metabolism - glycerolipid

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: nucleoplasm; endoplasmic reticulum membrane; extrinsic to membrane; plasma membrane; synapse; cytosol

Molecular Function: protein homodimerization activity; acylglycerol lipase activity; lipid binding; lysophospholipase activity

Biological Process: platelet activation; glycerophospholipid biosynthetic process; regulation of signal transduction; regulation of axon extension; phospholipid metabolic process; triacylglycerol catabolic process; regulation of inflammatory response; arachidonic acid metabolic process; regulation of sensory perception of pain; lipid metabolic process; blood coagulation; inflammatory response; fatty acid biosynthetic process; acylglycerol catabolic process

Research Articles on MGL

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Product Notes

The Mouse MGL mgll (Catalog #AAA051959) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA051959 ELISA Kit recognizes Mouse MGL. It is sometimes possible for the material contained within the vial of "Lipase, Monoacylglycerol, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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