Human Meteorin ELISA Kit | METRN elisa kit

Human Meteorin ELISA Kit

Cat. Num. AAA765674

• Gene Names: METRN; C16orf23; c380A1.2
• Reactivity: Human
• Synonyms: Meteorin; Human Meteorin ELISA Kit; METRN/Meteorin; METRN elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of METRN. No significant cross-reactivity or interference between METRN and analogues was observed.
• Sequence Length: 293

• Samples: Serum, plasma, tissue homogenates and other biological fluids
• Assay Type: Quantitative Sandwich
• Detection Range: 15.625-1000pg/ml
• Sensitivity: 9.375pg/ml
• Intra-assay Precision: CV<8%
• Inter-assay Precision: CV<10%
• Preparation and Storage: Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for METRN elisa kit

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the target amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of target can be calculated.

NCBI and Uniprot Product Information

• NCBI GI #: 13129000
• NCBI GeneID: 79006
• NCBI Accession #: NP_076947.1
• NCBI GenBank Nucleotide #: NM_024042.2
• Molecular Weight: 31,207 Da
• NCBI Official Full Name: meteorin
• NCBI Official Synonym Full Names: meteorin, glial cell differentiation regulator
• NCBI Official Symbol: METRN
• NCBI Official Synonym Symbols: C16orf23; c380A1.2
• NCBI Protein Information: meteorin
• UniProt Protein Name: Meteorin
• Protein Family: Meteorin
• UniProt Gene Name: METRN
• UniProt Synonym Gene Names: C16orf23
• UniProt Entry Name: METRN_HUMAN

NCBI Description

Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 [PubMed 15085178]).[supplied by OMIM, Mar 2008]

Uniprot Description

METRN: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Belongs to the meteorin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space

Biological Process: glial cell differentiation; positive regulation of axonogenesis