Methylmalonyl-CoA Epimerase/MCEE Recombinant Protein | MCEE recombinant protein
Recombinant Human Methylmalonyl-CoA Epimerase/MCEE Protein (C-6His)
Gene Names
MCEE; GLOD2
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Methylmalonyl-CoA Epimerase/MCEE; Recombinant Human Methylmalonyl-CoA Epimerase/MCEE Protein (C-6His); Methylmalonyl-CoA epimerase; mitochondrial; DL-methylmalonyl-CoA racemase; MCEE recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM Tris HCl, 150mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Sequence Positions
Gln37-Ala176
Sequence Length
176
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for MCEE recombinant protein
Methylmalonyl-CoA epimerase, mitochondrial(MCEE)is an enzyme which belongs to the glyoxalase I family. It converts (S)-methylmalonyl-CoA to the (R) form, catalyses the following chemical reaction: (R)-methylmalonyl-CoA (S)-methylmalonyl-CoA. It plays an important role in the catabolism of fatty acids with odd-length carbon chains. This protein deficiency is an autosomal recessive inborn error of AA metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria can appear in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 16.0 kDa
Actual Protein Molecular Mass: 18-20 kDa
Actual Protein Molecular Mass: 18-20 kDa
NCBI Official Full Name
methylmalonyl-CoA epimerase, mitochondrial
NCBI Official Synonym Full Names
methylmalonyl-CoA epimerase
NCBI Official Symbol
MCEE
NCBI Official Synonym Symbols
GLOD2
NCBI Protein Information
methylmalonyl-CoA epimerase, mitochondrial
UniProt Protein Name
Methylmalonyl-CoA epimerase, mitochondrial
UniProt Gene Name
MCEE
NCBI Description
The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. [provided by RefSeq, Jul 2008]
Research Articles on MCEE
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Product Notes
The MCEE mcee (Catalog #AAA2552959) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Gln37-Ala176. It is sometimes possible for the material contained within the vial of "Methylmalonyl-CoA Epimerase/MCEE, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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