Melanocortin receptor 4 (Mc4r) Recombinant Protein | Mc4r recombinant protein

Recombinant Mouse Melanocortin receptor 4 (Mc4r), partial

• Gene Names: Mc4r; Pkcp; Mc4-r
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Melanocortin receptor 4 (Mc4r); Recombinant Mouse Melanocortin receptor 4 (Mc4r); partial; Mc4r recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 332

• Species: Mus musculus (Mouse)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 85861190
• NCBI GeneID: 17202
• NCBI Accession #: NP_058673.2
• NCBI GenBank Nucleotide #: NM_016977.4
• UniProt Accession #: P56450; Q49NR4; Q9EQM7
• Molecular Weight: 36,959 Da
• NCBI Official Full Name: melanocortin receptor 4
• NCBI Official Synonym Full Names: melanocortin 4 receptor
• NCBI Official Symbol: Mc4r
• NCBI Official Synonym Symbols: Pkcp; Mc4-r
• NCBI Protein Information: melanocortin receptor 4
• UniProt Protein Name: Melanocortin receptor 4
• Protein Family: Melanocortin receptor
• UniProt Gene Name: Mc4r
• UniProt Synonym Gene Names: MC4-R

NCBI Description

This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors, which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As part of the central nervous melanocortin system, the encoded protein is competitively bound by either melanocyte stimulating hormone or agouti-related protein to regulate energy homeostasis. Disruption of this gene promotes hyperphagia and obesity, and is associated with increased cholesterol levels and insulin resistance. [provided by RefSeq, Dec 2012]

Uniprot Description

Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).