Methionine Adenosyltransferase II Beta Recombinant Protein | MAT2b recombinant protein

Recombinant Methionine Adenosyltransferase II Beta (MAT2b)

Cat. Num. AAA2123818

• Gene Names: MAT2B; TGR; MAT-II; SDR23E1; MATIIbeta; Nbla02999
• Applications: SDS-Page, Western Blot
• Purity: >90%
• Synonyms: Methionine Adenosyltransferase II Beta; Recombinant Methionine Adenosyltransferase II Beta (MAT2b); MATIIbeta; TGR; SDR23E1; Short Chain Dehydrogenase/Reductase Family 23E; Member 1; Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase; MAT2b recombinant protein

• Host: E Coli
• Purity/Purification: >90%
• Form/Format: Freeze-dried powder; PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Sequence Positions: Met1~His334
• Sequence Length: 334

• Applicable Applications for MAT2b recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Source: Prokaryotic expression
• Species: Human
• Tag: N-terminal His Tag
• Isoelectric Point: 6.9
• Reconstitution: Reconstitute in PBS or others.
• Preparation and Storage: Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.; Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for MAT2b recombinant protein

Enzyme & Kinase

NCBI and Uniprot Product Information

• NCBI GI #: 74719662
• NCBI GeneID: 27430
• UniProt Accession #: Q9NZL9
• Molecular Weight: Predicted Molecular Mass: 41.3kDa; Accurate Molecular Mass: 43kDa
• NCBI Official Full Name: Methionine adenosyltransferase 2 subunit beta
• NCBI Official Synonym Full Names: methionine adenosyltransferase 2B
• NCBI Official Symbol: MAT2B
• NCBI Official Synonym Symbols: TGR; MAT-II; SDR23E1; MATIIbeta; Nbla02999
• NCBI Protein Information: methionine adenosyltransferase 2 subunit beta
• UniProt Protein Name: Methionine adenosyltransferase 2 subunit beta
• Protein Family: Methionine adenosyltransferase
• UniProt Gene Name: MAT2B
• UniProt Synonym Gene Names: TGR; MAT II beta
• UniProt Entry Name: MAT2B_HUMAN

NCBI Description

The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

Uniprot Description

MAT2B: Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S- adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S- adenosylmethionine inhibition. Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; Other Amino Acids Metabolism - selenoamino acid; Amino Acid Metabolism - cysteine and methionine

Chromosomal Location of Human Ortholog: 5q34

Cellular Component: methionine adenosyltransferase complex; mitochondrion; intracellular; cytosol; nucleus

Molecular Function: enzyme binding; methionine adenosyltransferase regulator activity

Biological Process: methylation; regulation of catalytic activity; xenobiotic metabolic process; S-adenosylmethionine biosynthetic process; one-carbon compound metabolic process