MARCH-VII / Axotrophin Blocking Peptide | MARCH7 blocking peptide
MARCH-VII / Axotrophin Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]
Uniprot Description
MARCH7: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Protein type: EC 6.3.2.-; Ubiquitin conjugating system; EC 6.3.2.19; Ubiquitin ligase; Ligase
Chromosomal Location of Human Ortholog: 2q24.2
Molecular Function: ligase activity; zinc ion binding
Biological Process: negative regulation of T cell proliferation; protein ubiquitination; regulation of tolerance induction
Research Articles on MARCH7
Similar Products
Product Notes
The MARCH7 march7 (Catalog #AAA426812) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The MARCH-VII / Axotrophin Immunizing Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-NFNQESEG RNT. It is sometimes possible for the material contained within the vial of "MARCH-VII / Axotrophin, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
