Inhibin beta C Chain (INHBC) Active Protein | INHBC active protein
Recombinant Human Inhibin beta C Chain (INHBC)
Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]
Uniprot Description
INHBC: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.1
Cellular Component: extracellular space; extracellular region
Molecular Function: growth factor activity; hormone activity; cytokine activity; transforming growth factor beta receptor binding
Biological Process: regulation of apoptosis; regulation of MAPKKK cascade; cell development; growth
Research Articles on INHBC
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Product Notes
The INHBC inhbc (Catalog #AAA7115148) is an Active Protein produced from Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-352aa; Full Length of Mature Protein. The amino acid sequence is listed below: TPRAGGQCPA CGGPTLELES QRELLLDLAK RSILDKLHLT QRPTLNRPVS RAALRTALQH LHGVPQGALL EDNREQECEI ISFAETGLST INQTRLDFHF SSDRTAGDRE VQQASLMFFV QLPSNTTWTL KVRVLVLGPH NTNLTLATQY LLEVDASGWH QLPLGPEAQA ACSQGHLTLE LVLEGQVAQS SVILGGAAHR PFVAARVRVG GKHQIHRRGI DCQGGSRMCC RQEFFVDFRE IGWHDWIIQP EGYAMNFCIG QCPLHIAGMP GIAASFHTAV LNLLKANTAA GTTGGGSCCV PTARRPLSLL YYDRDSNIVK TDIPDMVVEA CGCS. It is sometimes possible for the material contained within the vial of "Inhibin beta C Chain (INHBC), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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