Protein maelstrom (mael) Recombinant Protein | mael recombinant protein
Recombinant Drosophila simulans Protein maelstrom (mael)
NCBI and Uniprot Product Information
Uniprot Description
Involved both in the piRNA and miRNA metabolic processes. As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons. As a nuclear component, it is required for proper differentiation in the germline stem cell (GSC) lineage by repressing microRNA-7 (miR-7), thereby acting as an indirect regulator of bag-of-marbles (Bam). Acts by binding to the promoter of miR-7 gene and repressing its expression; miR-7 repression alleviates the Bam repression by miR-7, thereby allowing differentiation in the germline stem cell (GSC) lineage ().
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Product Notes
The mael mael (Catalog #AAA1093528) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-394, Full length protein. The amino acid sequence is listed below: MAPKKQNGFM MFVNEWRNRN AEGRRMTLAE AVYHCGTIWE KMDTQQRGPY NSDAKDANAA RRDKRGSLNG HGQVDKAQRE AAESLMDKAQ REAAESLMDM KRTTERLVLN AKMSHDLENA KFVFVAFNYF TKALTTDVYV PAEFAACEYS LKEGIRSIYS TMIDPGQIIF GQGSDALHNS STTHDLPLPP NALGEKNMVK LYRNILDYLT KCQGEGKTPI VFTPAENIGM VKSCFRYLEC EDDSRDGGGK IEVFDIQYLL FILKKEVMSV AGLNDEKINK FATDAFFKND FFEFTAGIAC QISSINTRDY HVATLIGLLP AQTINVYLGS TLRSMHEVLS DNDTKLTGYI SFLFEVICGV ALMFWVLQKA RKELSETLLS ADYNNEGKHP DVQV. It is sometimes possible for the material contained within the vial of "Protein maelstrom (mael), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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