Mitotic spindle assembly checkpoint protein MAD2B (mad2l2) Recombinant Protein | mad2l2 recombinant protein
Recombinant Danio rerio Mitotic spindle assembly checkpoint protein MAD2B (mad2l2)
NCBI and Uniprot Product Information
Uniprot Description
Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation ().
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Product Notes
The mad2l2 mad2l2 (Catalog #AAA1431699) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-211, Full length protein. The amino acid sequence is listed below: MATLTRQDLN FGQVVADILC EFLEVAIHLI LYVRDIYPSG IFQKRQKYNV PVQMSCHPQL NQYIQDTLHC VKPLIEKNEA EKVVVVIMNK EHHPVERFVF EISQPPLLAI SSETLLSHVE QLLRAMILKI SVCDAVLDSN PPGCTFTVLV HTREAATRNM EKVQVIKDFP WIVADEQEVH MEEAKLIPLK TMTSDILKMQ LYVEEKTQKS S. It is sometimes possible for the material contained within the vial of "Mitotic spindle assembly checkpoint protein MAD2B (mad2l2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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