Rat microtubule-actin crosslinking factor 1 ELISA Kit | MACF1 elisa kit
Rat Microtubule-actin cross-linking factor 1, isoform 4, MACF1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ACF7 iso2: F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity)
Protein type: Motility/polarity/chemotaxis; Cytoskeletal; Actin-binding
Cellular Component: microtubule cytoskeleton; Golgi apparatus; microtubule; membrane; cell; cytoplasm; plasma membrane; intracellular; actin cytoskeleton
Molecular Function: protein binding; microtubule binding; ATPase activity; calcium ion binding; actin binding
Biological Process: regulation of microtubule-based process; Wnt receptor signaling pathway; mesoderm formation; wound healing; metabolic process; positive regulation of axon extension; Golgi to plasma membrane protein transport; regulation of focal adhesion formation; establishment and/or maintenance of cell polarity; posttranslational protein targeting to membrane; cell cycle arrest; positive regulation of Wnt receptor signaling pathway
Research Articles on MACF1
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Product Notes
The Rat MACF1 macf1 (Catalog #AAA9326787) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326787 ELISA Kit recognizes Rat MACF1. It is sometimes possible for the material contained within the vial of "microtubule-actin crosslinking factor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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