LSAMP recombinant protein

Recombinant Human LSAMP Protein

Cat. Num. AAA8249407

• Gene Names: LSAMP; LAMP; IGLON3
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: LSAMP; Recombinant Human LSAMP Protein; IGLON3; LAMP; Limbic system-associated membrane protein; IgLON family member 3; LSAMP recombinant protein

• Host: Human cells
• Reactivity: Human
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 uM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence: VRSVDFNRGT DNITVRQGDT AILRCVVEDK NSKVAWLNRS GIIFAGHDKW SLDPRVELEK RHSLEYSLRI QKVDVYDEGS YTCSVQTQHE PKTSQVYLIV QVPPKISNIS SDVTVNEGSN VTLVCMANGR PEPVITWRHL TPTGREFEGE EEYLEILGIT REQSGKYECK AANEVSSADV KQVKVTVNYP PTITESKSNE ATTGRQASLK CEASAVPAPD FEWYRDDTRI NSANGLEIKS TEGQSSLTVT NVTEEHYGNY TCVAANKLGV TNASLVLFRP GSVRGINVDH HHHHH
• Sequence Length: 361

• Applicable Applications for LSAMP recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: < 0.1 ng/mug (1 IEU/ug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.

Related Product Information for LSAMP recombinant protein

Recombinant Human LSAMP Protein is produced by our mammalian expression system and the target gene encoding Val29-Asn315 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 974576775
• NCBI GeneID: 4045
• NCBI Accession #: NP_001305844.1
• NCBI GenBank Nucleotide #: NM_001318915.1
• UniProt Accession #: Q13449; Q8IV49
• NCBI Official Full Name: limbic system-associated membrane protein isoform 2
• NCBI Official Synonym Full Names: limbic system-associated membrane protein
• NCBI Official Symbol: LSAMP
• NCBI Official Synonym Symbols: LAMP; IGLON3
• NCBI Protein Information: limbic system-associated membrane protein
• UniProt Protein Name: Limbic system-associated membrane protein
• UniProt Gene Name: LSAMP
• UniProt Synonym Gene Names: IGLON3; LAMP; LSAMP
• UniProt Entry Name: LSAMP_HUMAN

NCBI Description

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

LSAMP: Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection. Belongs to the immunoglobulin superfamily. IgLON family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3q13.2-q21

Molecular Function: protein binding

Biological Process: nervous system development