LRP12 recombinant protein

Recombinant Human LRP12 Protein

Cat. Num. AAA8249402

• Gene Names: LRP12; ST7
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Synonyms: LRP12; Recombinant Human LRP12 Protein; ST7; Low-density lipoprotein receptor-related protein 12; LRP-12; Suppressor of tumorigenicity 7 protein; LRP12 recombinant protein

• Host: Human cells
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Sequence: NGALAEHSEN VHISGVSTAC GETPEQIRAP SGIITSPGWP SEYPAKINCS WFIRANPGEI ITISFQDFDI QGSRRCNLDW LTIETYKNIE SYRACGSTIP PPYISSQDHI WIRFHSDDNI SRKGFRLAYF SGKSEEPNCA CDQFRCGNGK CIPEAWKCNN MDECGDSSDE EICAKEANPP TAAAFQPCAY NQFQCLSRFT KVYTCLPESL KCDGNIDCLD LGDEIDCDVP TCGQWLKYFY GTFNSPNYPD FYPPGSNCTW LIDTGDHRKV ILRFTDFKLD GTGYGDYVKI YDGLEENPHK LLRVLTAFDS HAPLTVVSSS GQIRVHFCAD KVNAARGFNA TYQVDGFCLP WEIPCGGNWG CYTEQQRCDG YWHCPNGRDE TNCTMCQKEE FPCSRNGVCY PRSDRCNYQN HCPNGSDEKN CFFCQPGNFH CKNNRCVFES WVCDSQDDCG DGSDEENCPV IVDHHHHHH
• Sequence Length: 840

• Applicable Applications for LRP12 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for LRP12 recombinant protein

Recombinant Human LRP12 Protein is produced by our Mammalian expression system and the target gene encoding Asn28-Ile488 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 208973262
• NCBI GeneID: 29967
• NCBI Accession #: NP_001129175.1
• NCBI GenBank Nucleotide #: NM_001135703.2
• UniProt Accession #: Q9Y561; A8K137; B4DRQ2
• Molecular Weight: 93,123 Da
• NCBI Official Full Name: low-density lipoprotein receptor-related protein 12 isoform b
• NCBI Official Synonym Full Names: LDL receptor related protein 12
• NCBI Official Symbol: LRP12
• NCBI Official Synonym Symbols: ST7
• NCBI Protein Information: low-density lipoprotein receptor-related protein 12
• UniProt Protein Name: Low-density lipoprotein receptor-related protein 12
• Protein Family: Low-density lipoprotein receptor-related protein
• UniProt Gene Name: LRP12
• UniProt Synonym Gene Names: ST7; LRP-12
• UniProt Entry Name: LRP12_HUMAN

NCBI Description

This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Uniprot Description

LRP12: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. Belongs to the LDLR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: integral to plasma membrane

Molecular Function: protein binding