Leukotoxin translocation ATP-binding protein LktB (lktB) Recombinant Protein | lktB recombinant protein

Recombinant Pasteurella haemolytica Leukotoxin translocation ATP-binding protein LktB (lktB)

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Leukotoxin translocation ATP-binding protein LktB (lktB); Recombinant Pasteurella haemolytica Leukotoxin translocation ATP-binding protein LktB (lktB); Recombinant Leukotoxin translocation ATP-binding protein LktB (lktB); Leukotoxin translocation ATP-binding protein LktB EC= 3.6.3.43; lktB recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-708
• Sequence: MEANHQRNDLGLVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLVNLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSRASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSSSFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISVTRLGDVLNSPTEQYQGKLSLPEIKGDISFKNIRFRYKPDAPTILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYLHQLQLN
• Sequence Length: 708

• Species: Pasteurella haemolytica (Mannheimia haemolytica)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 73621171
• UniProt Accession #: P0C086; Q934A3
• Molecular Weight: 79,699 Da
• NCBI Official Full Name: Leukotoxin translocation ATP-binding protein LktB
• UniProt Protein Name: Leukotoxin translocation ATP-binding protein LktB
• Protein Family: Leukotoxin translocation ATP-binding protein
• UniProt Gene Name: lktB
• UniProt Entry Name: LKTB7_PASHA

Uniprot Description

Function: Part of the ABC transporter complex LktBD involved in leukotoxin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation

Probable.

Catalytic activity: ATP + H2O + peptide(In) = ADP + phosphate + peptide(Out).

Subunit structure: Homodimer

By similarity.

Subcellular location: Cell inner membrane; Multi-pass membrane protein

Probable.

Domain: In LktB the peptidase C39 domain, the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.

Sequence similarities: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family. [View classification]Contains 1 ABC transmembrane type-1 domain.Contains 1 ABC transporter domain.Contains 1 peptidase C39 domain.

Caution: Leu-10 is present instead of the conserved Cys which is expected to be the active site residue of peptidase C39. Thus this protein is presumed to be without peptidase activity.