Human Lck interacting transmembrane adaptor 1 ELISA Kit | LIME1 elisa kit
Human Lck-interacting transmembrane adapter 1, LIME1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
LIME1 is a raft-associated transmembrane adaptor phosphoprotein that is preferentially expressed in hemopoietic cells, particularly T cells (Brdickova et al., 2003 [PubMed 14610046]; Hur et al., 2003 [PubMed 14610044]).[supplied by OMIM, Mar 2008]
Uniprot Description
LIME1: Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 20q13.3
Cellular Component: extracellular space; plasma membrane; integral to membrane
Biological Process: B cell receptor signaling pathway; T cell receptor signaling pathway
Research Articles on LIME1
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Product Notes
The Human LIME1 lime1 (Catalog #AAA9340878) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340878 ELISA Kit recognizes Human LIME1. It is sometimes possible for the material contained within the vial of "Lck interacting transmembrane adaptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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