Late protein H2 (H2R, I2R) Recombinant Protein | I2R recombinant protein
Recombinant Variola virus Late protein H2 (H2R, I2R)
NCBI and Uniprot Product Information
Uniprot Description
Function: Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation)
By similarity.
Subunit structure: Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex
By similarity.
Subcellular location: Virion membrane; Single-pass type III membrane protein
Potential. Note: Component of the mature virion (MV) membrane
By similarity. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis
By similarity.
Post-translational modification: Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes
By similarity.
Sequence similarities: Belongs to the poxviridae H2 family.
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Product Notes
The I2R (Catalog #AAA1164173) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-189. The amino acid sequence is listed below: MDKTTLSVNA CNLEYVREKA IVGVQAAKTS TLIFFVIILA ISALLLWFQT SDNPVFNELT RYMRIKNTVN DWKSLTDSKT KLESDRGRLL AAGKDDIFEF KCVDFGAYFI AMRLDKKTYL PQAIRRGTGD AWMVKKAAKV DPSAQQFCQY LIKHKSNNVI TCGNEMLNEL GYSGYFMSPH WCSDLSNME. It is sometimes possible for the material contained within the vial of "Late protein H2 (H2R, I2R), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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