Laminin subunit alpha-2 (LAMA2) Recombinant Protein | LAMA2 recombinant protein

Recombinant Human Laminin subunit alpha-2 (LAMA2) , partial

Cat. Num. AAA949425

• Gene Names: LAMA2; LAMM
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Laminin subunit alpha-2 (LAMA2); Recombinant Human Laminin subunit alpha-2 (LAMA2); partial; LAMA2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 3122

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for LAMA2 recombinant protein

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 28559088
• NCBI GeneID: 3908
• NCBI Accession #: NP_000417.2
• NCBI GenBank Nucleotide #: NM_000426.3
• UniProt Accession #: P24043; Q14736; Q5VUM2; Q93022
• Molecular Weight: 343,905 Da
• NCBI Official Full Name: laminin subunit alpha-2 isoform a
• NCBI Official Synonym Full Names: laminin subunit alpha 2
• NCBI Official Symbol: LAMA2
• NCBI Official Synonym Symbols: LAMM
• NCBI Protein Information: laminin subunit alpha-2
• UniProt Protein Name: Laminin subunit alpha-2
• Protein Family: Laminin
• UniProt Gene Name: LAMA2
• UniProt Synonym Gene Names: LAMM

NCBI Description

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.