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SDS-Page

LAIR2 recombinant protein

LAIR2, 22-135aa, Human, His tag, E Coli

Gene Names
LAIR2; CD306
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
LAIR2; 22-135aa; Human; His tag; E Coli; Leukocyte-associated immunoglobulin-like receptor; CD306; LAIR2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Concentration
1mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQEGAL PRPSISAEPG TVISPGSHVT FMCRGPVGVQ TFRLEREDRA KYKDSYNVFR LGPSESEARF HIDSVSEGNA GLYRCLYYKP PGWSEHSDFL ELLVKGTVPG TEASGFDAP
Sequence Length
135
Applicable Applications for LAIR2 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for LAIR2 recombinant protein
LAIR2, also known as leukocyte-associated immunoglobulin-like receptor 2, is a secreted, 131 amino acid (aa) protein that contains one IglikeC2 type domain, making it a member of the Ig superfamily. Although one is secreted and one is membranebound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similaradhesion profiles. This suggests that LAIR2 may compete with LAIR1 for ligand binding. Recombinant human LAIR2 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for LAIR2 recombinant protein
References
Meyaard L., et al. (1997) Immunity. 7:283-290; Meyaard L., et al. (1999) J. Immunol. 162:5800-5804

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15.2 kDa (139aa) confirmed by MALDI-TOF
NCBI Official Full Name
leukocyte-associated immunoglobulin-like receptor 2 isoform b
NCBI Official Synonym Full Names
leukocyte associated immunoglobulin like receptor 2
NCBI Official Symbol
LAIR2
NCBI Official Synonym Symbols
CD306
NCBI Protein Information
leukocyte-associated immunoglobulin-like receptor 2
UniProt Protein Name
Leukocyte-associated immunoglobulin-like receptor 2
UniProt Gene Name
LAIR2
UniProt Synonym Gene Names
CD306; LAIR-2

NCBI Description

The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]

Research Articles on LAIR2

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Product Notes

The LAIR2 lair2 (Catalog #AAA204179) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's LAIR2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the LAIR2 lair2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMQEGAL PRPSISAEPG TVISPGSHVT FMCRGPVGVQ TFRLEREDRA KYKDSYNVFR LGPSESEARF HIDSVSEGNA GLYRCLYYKP PGWSEHSDFL ELLVKGTVPG TEASGFDAP. It is sometimes possible for the material contained within the vial of "LAIR2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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