Target of rapamycin complex 1 subunit KOG1 (KOG1) Recombinant Protein | KOG1 recombinant protein

Recombinant Saccharomyces cerevisiae Target of rapamycin complex 1 subunit KOG1 (KOG1) , partial

• Gene Names: KOG1; LAS24
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Target of rapamycin complex 1 subunit KOG1 (KOG1); Recombinant Saccharomyces cerevisiae Target of rapamycin complex 1 subunit KOG1 (KOG1); partial; KOG1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,557

• Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 6321980
• NCBI GeneID: 856593
• NCBI Accession #: NP_012056.1
• NCBI GenBank Nucleotide #: NM_001179317.1
• UniProt Accession #: P38873; D3DLD4
• Molecular Weight: 177,609 Da
• NCBI Official Full Name: ubiquitin-binding TORC1 subunit KOG1
• NCBI Official Symbol: KOG1
• NCBI Official Synonym Symbols: LAS24
• NCBI Protein Information: ubiquitin-binding TORC1 subunit KOG1
• UniProt Protein Name: Target of rapamycin complex 1 subunit KOG1
• Protein Family: Target of rapamycin complex
• UniProt Gene Name: KOG1
• UniProt Synonym Gene Names: LAS24; TORC1 subunit KOG1

Uniprot Description

Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions. KOG1 may have a role in binding and recruiting substrates of TORC1.