KLF5 recombinant protein

Recombinant Human KLF5 protein

Cat. Num. AAA1562432

• Gene Names: KLF5; CKLF; IKLF; BTEB2
• Purity: >90% as determined by SDS-PAGE
• Synonyms: KLF5; Recombinant Human KLF5 protein; Krueppel-like factor 5; Basic transcription element-binding protein 2; Short name:BTE-binding protein 2; Colon krueppel-like factor; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2; KLF5 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Species: Homo sapiens (Human)
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Related Product Information for KLF5 recombinant protein

Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.

Product Categories/Family for KLF5 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 12644412
• NCBI GeneID: 688
• UniProt Accession #: Q13887; Q9UHP8; L0R3U5; L0R4T9
• Molecular Weight: 457
• NCBI Official Full Name: Krueppel-like factor 5
• NCBI Official Synonym Full Names: Kruppel-like factor 5 (intestinal)
• NCBI Official Symbol: KLF5
• NCBI Official Synonym Symbols: CKLF; IKLF; BTEB2
• NCBI Protein Information: Krueppel-like factor 5; Klf5C isoform; BTE-binding protein 2; GC box binding protein 2; colon kruppel-like factor; colon krueppel-like factor; transcription factor BTEB2; intestinal-enriched kruppel-like factor; intestinal-enriched krueppel-like factor; b
• UniProt Protein Name: Krueppel-like factor 5
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF5
• UniProt Synonym Gene Names: BTEB2; CKLF; IKLF; BTE-binding protein 2
• UniProt Entry Name: KLF5_HUMAN

NCBI Description

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Uniprot Description

KLF5: Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q22.1

Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; cytoplasm; plasma membrane

Molecular Function: protein binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; microvillus biogenesis; positive regulation of cell proliferation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; regulation of microvillus biogenesis