Dyslexia-associated protein KIAA0319 (KIAA0319) Recombinant Protein | KIAA0319 recombinant protein

Recombinant Human Dyslexia-associated protein KIAA0319 (KIAA0319) , partial

• Gene Names: KIAA0319; AAVR; DYX2; NMIG; DYLX2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Dyslexia-associated protein KIAA0319 (KIAA0319); Recombinant Human Dyslexia-associated protein KIAA0319 (KIAA0319); partial; KIAA0319 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,011

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 270265853
• NCBI GeneID: 9856
• NCBI Accession #: NP_001161846.1
• NCBI GenBank Nucleotide #: NM_001168374.1
• UniProt Accession #: Q5VV43; Q9UJC8; Q9Y4G7; A7MD37; B2RTU7; B4DHA7; B4DK75; B7ZML3; F5H123
• Molecular Weight: 110,370 Da
• NCBI Official Full Name: dyslexia-associated protein KIAA0319 isoform b
• NCBI Official Synonym Full Names: KIAA0319
• NCBI Official Symbol: KIAA0319
• NCBI Official Synonym Symbols: AAVR; DYX2; NMIG; DYLX2
• NCBI Protein Information: dyslexia-associated protein KIAA0319
• UniProt Protein Name: Dyslexia-associated protein KIAA0319
• Protein Family: Dyslexia-associated protein
• UniProt Gene Name: KIAA0319

NCBI Description

This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites.