Lysine-specific demethylase 4C (Kdm4c) Recombinant Protein | Kdm4c recombinant protein
Recombinant Mouse Lysine-specific demethylase 4C (Kdm4c) , partial
Gene Names
Kdm4c; Gasc1; Jmjd2c; AA517467; 2410141F18Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Lysine-specific demethylase 4C (Kdm4c); Recombinant Mouse Lysine-specific demethylase 4C (Kdm4c); partial; Kdm4c recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
1,054
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Kdm4c recombinant protein
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
119,966 Da
NCBI Official Full Name
lysine-specific demethylase 4C isoform 2
NCBI Official Synonym Full Names
lysine (K)-specific demethylase 4C
NCBI Official Symbol
Kdm4c
NCBI Official Synonym Symbols
Gasc1; Jmjd2c; AA517467; 2410141F18Rik
NCBI Protein Information
lysine-specific demethylase 4C
UniProt Protein Name
Lysine-specific demethylase 4C
Protein Family
UniProt Gene Name
Kdm4c
UniProt Synonym Gene Names
Jhdm3c; Jmjd2c; Kiaa0780
Uniprot Description
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate ().
Research Articles on Kdm4c
Similar Products
Product Notes
The Kdm4c kdm4c (Catalog #AAA1352683) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lysine-specific demethylase 4C (Kdm4c), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
