Human lysine (K) -specific demethylase 4B ELISA Kit | KDM4B elisa kit

Human Lysine-specific demethylase 4B, KDM4B ELISA Kit

Cat. Num. AAA9316686

• Gene Names: KDM4B; JMJD2B; TDRD14B
• Reactivity: Human
• Synonyms: lysine (K) -specific demethylase 4B; Human Lysine-specific demethylase 4B; KDM4B ELISA Kit; Human Lysine-specific demethylase 4B (KDM4B) ELISA kit; FLJ44906; JMJD2B; KIAA0876; jumonji domain containing 2B; KDM4B elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 62.5pg/ml-2000pg/ml
• Sensitivity: 10pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for KDM4B elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of KDM4B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 45504380
• NCBI GeneID: 23030
• NCBI Accession #: NP_055830.1
• NCBI GenBank Nucleotide #: NM_015015.2
• UniProt Accession #: O94953; O75274; Q6P3R5; Q9P1V1; Q9UF40; B9EGN8; D6W631
• Molecular Weight: 121,897 Da
• NCBI Official Full Name: lysine-specific demethylase 4B
• NCBI Official Synonym Full Names: lysine (K)-specific demethylase 4B
• NCBI Official Symbol: KDM4B
• NCBI Official Synonym Symbols: JMJD2B; TDRD14B
• NCBI Protein Information: lysine-specific demethylase 4B; tudor domain containing 14B; jumonji domain containing 2B; jumonji domain-containing protein 2B; jmjC domain-containing histone demethylation protein 3B
• UniProt Protein Name: Lysine-specific demethylase 4B
• Protein Family: Lysine-specific demethylase
• UniProt Gene Name: KDM4B
• UniProt Synonym Gene Names: JHDM3B; JMJD2B; KIAA0876
• UniProt Entry Name: KDM4B_HUMAN

Uniprot Description

JMJD2B: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Belongs to the JHDM3 histone demethylase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.11.-; Oxidoreductase; Demethylase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; focal adhesion; cell junction; nucleus

Molecular Function: zinc ion binding; dioxygenase activity

Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent; chromatin modification