Mouse lysine (K) -specific demethylase 2A ELISA Kit | KDM2A elisa kit
Mouse Lysine-specific demethylase 2A, KDM2A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
FBXL11: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Belongs to the JHDM1 histone demethylase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; Demethylase; EC 1.14.11.27
Cellular Component: nuclear chromatin; nucleolus; nucleus
Molecular Function: DNA binding; zinc ion binding; unmethylated CpG binding; dioxygenase activity; metal ion binding; histone demethylase activity (H3-K36 specific); oxidoreductase activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; chromatin modification; double-strand break repair via nonhomologous end joining
Research Articles on KDM2A
Similar Products
Product Notes
The Mouse KDM2A kdm2a (Catalog #AAA9339530) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339530 ELISA Kit recognizes Mouse KDM2A. It is sometimes possible for the material contained within the vial of "lysine (K) -specific demethylase 2A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
