Small conductance calcium-activated potassium channel protein 3 (KCNN3) Recombinant Protein | KCNN3 recombinant protein
Recombinant Pig Small conductance calcium-activated potassium channel protein 3 (KCNN3)
NCBI and Uniprot Product Information
Uniprot Description
Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin
By similarity.
Subunit structure: Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding
By similarity.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
Research Articles on KCNN3
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Product Notes
The KCNN3 kcnn3 (Catalog #AAA958282) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-724. The amino acid sequence is listed below: MDTSGHFHDS GVGDLDEDPK CPCPSSGDEQ QQQQPPPPPP PPAPPAAPQQ PPGPPLQPQP LQLQQQQQQQ QQQPPHPLSQ LAQLQSQPVH PGLLHSSPTA FRAPPSSNST AILHPSSRQG SQLNLNDHLL GHSPSSTATS GPGGGGRHRQ ASPLVHRRDS NPFTEIAMSS CKYSGGVMKP LSRLSASRRN LIEAEPEGQP LQLFSPSNPP EIIISSREDN HAHQTLLHHP NATHNHQHAG TTASSTTFPK ANKRKNQNIG YKLGHRRALF EKRKRLSDYA LIFGMFGIVV MVIETELSWG LYSKDSMFSL ALKCLISLST IILLGLIIAY HTREVQLFVI DNGADDWRIA MTYERILYIS LEMLVCAIHP IPGEYKFFWT ARLAFSYTPS RAEADVDIIL SIPMFLRLYL IARVMLLHSK LFTDASSRSI GALNKINFNT RFVMKTLMTI CPGTVLLVFS ISLWIIAAWT VRVCERYHDQ QDVTSNFLGA MWLISITFLS IGYGDMVPHT YCGKGVCLLT GIMGAGCTAL VVAVVARKLE LTKAEKHVHN FMMDTQLTKR IKNAAANVLR ETWLIYKHTK LLKKIDHAKV RKHQRKFLQA IHQLRSVKME QRKLSDQANT LVDLSKMQNV MYDLITELND RSEDLEKQIG SLESKLEHLT ASFNSLPLLI ADTLRQQQQQ LLSALMEARG VSVAVGTTHT PLSDSPIGVS STSFPTPYTS SSSC. It is sometimes possible for the material contained within the vial of "Small conductance calcium-activated potassium channel protein 3 (KCNN3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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