Human Potassium channel subfamily K member 13 ELISA Kit | KCNK13 elisa kit

Human Potassium channel subfamily K member 13 (KCNK13) ELISA Kit

Cat. Num. AAA280172

• Gene Names: KCNK13; THIK1; THIK-1; K2p13.1
• Reactivity: Human
• Synonyms: Potassium channel subfamily K member 13; Human Potassium channel subfamily K member 13 (KCNK13) ELISA Kit; KCNK13 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human KCNK13. No significant cross-reactivity or interference between Human KCNK13 and analogues was observed.
• Sequence Length: 408

• Samples: Serum, Plasma, Other biological fluids
• Assay Type: Sandwich
• Sample Volume: 1-200 uL
• Precision: Intra-assay Precision (Precision within an assay); Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.; Inter-assay Precision (Precision between assays); Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.; CV (%) = SD/meanX100; Intra-Assay: CV; Inter-Assay: CV
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for KCNK13 elisa kit

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KCNK13 in samples. An antibody specific for KCNK13 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNK13 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KCNK13 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KCNK13 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 16306555
• NCBI GeneID: 56659
• NCBI Accession #: NP_071337.2
• NCBI GenBank Nucleotide #: NM_022054.3
• UniProt Accession #: Q9HB14; Q96E79; B5TJL8
• Molecular Weight: 45,391 Da
• NCBI Official Full Name: potassium channel subfamily K member 13
• NCBI Official Synonym Full Names: potassium two pore domain channel subfamily K member 13
• NCBI Official Symbol: KCNK13
• NCBI Official Synonym Symbols: THIK1; THIK-1; K2p13.1
• NCBI Protein Information: potassium channel subfamily K member 13
• UniProt Protein Name: Potassium channel subfamily K member 13
• Protein Family: Potassium channel subfamily
• UniProt Gene Name: KCNK13
• UniProt Synonym Gene Names: THIK-1

NCBI Description

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]

Uniprot Description

KCNK13: Potassium channel displaying weak inward rectification in symmetrical K(+) solution. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q32.11

Cellular Component: integral component of plasma membrane; plasma membrane

Molecular Function: potassium channel activity; potassium ion leak channel activity; voltage-gated ion channel activity

Biological Process: stabilization of membrane potential