Rat katanin p60 (ATPase-containing) subunit A 1 ELISA Kit | KATNA1 elisa kit
Rat Katanin p60 ATPase-containing subunit A1, KATNA1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
p60 ATPase-containing subunit of katanin, a heterodimeric enzyme (together with p80 subunit Katnb1) responsible for severing microtubules from the centrosome [RGD, Feb 2006]
Uniprot Description
Function: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth 2 PublicationsManual assertion based on experiment in:Ref.1
Catalytic activity: ATP + H2O = ADP + phosphate.UniRule annotationHAMAP-Rule:MF_03023
Enzyme regulation: ATPase activity is stimulated by microtubules, which promote homooligomerization ATP-dependent microtubule severing is stimulated by interaction with KATNB1 UniRule annotationHAMAP-Rule:MF_03023
Research Articles on KATNA1
Similar Products
Product Notes
The Rat KATNA1 katna1 (Catalog #AAA9338612) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338612 ELISA Kit recognizes Rat KATNA1. It is sometimes possible for the material contained within the vial of "katanin p60 (ATPase-containing) subunit A 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
