Mouse katanin p60 (ATPase-containing) subunit A 1 ELISA Kit | KATNA1 elisa kit
Mouse Katanin p60 ATPase-containing subunit A1, KATNA1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
KATNA1: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body may allow their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Motility/polarity/chemotaxis; EC 3.6.4.3
Cellular Component: spindle pole; centrosome; microtubule; lipid particle; nucleoplasm; cytoskeleton; growth cone; cell soma; axon; cytoplasm; plasma membrane; microtubule organizing center; spindle; midbody; nucleus
Molecular Function: dynein binding; protein binding; hydrolase activity; protein heterodimerization activity; microtubule binding; ATPase activity; nucleotide binding; microtubule-severing ATPase activity; ATP binding
Biological Process: mitosis; protein localization; metabolic process; cell division; microtubule severing; neuron migration; cell cycle; microtubule bundle formation; cytoplasmic microtubule organization and biogenesis
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Product Notes
The Mouse KATNA1 katna1 (Catalog #AAA9326965) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326965 ELISA Kit recognizes Mouse KATNA1. It is sometimes possible for the material contained within the vial of "katanin p60 (ATPase-containing) subunit A 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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