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Structure

K 01-162, Inhibitor | K01-162, inhibitor

K 01-162

Purity
98.00%
Synonyms
K 01-162; K162; K01-162; inhibitor
Ordering
 
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For Research Use Only!
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 14.29mg/mL (49.59mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C15H14BrN
SMILES
BrC1=CC(CC2=C3C=CC(N(C)C)=C2)=C3C=C1
CAS Number
677746-25-7
Target & IC50
Others
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Structure

Related Product Information for K01-162, inhibitor
K 01-162 binds and destabilizes AbetaO (beta-amyloid), with an EC50 of 80nM.
References
Li J, et al. Alzheimer's disease drug candidates stabilize A-beta protein native structure by interacting with the hydrophobic core. Biophys J. 2011 Feb 16;100(4):1076-82.
Li J, et al. Alzheimer's disease drug candidates stabilize A-beta protein native structure by interacting with the hydrophobic core. Biophys J. 2011 Feb 16;100(4):1076-82.
Hong HS, et al. Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging. 2010 Oct;31(10):1690-9.
Hong HS, et al. Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging. 2010 Oct;31(10):1690-9.

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Product Notes

The K01-162 (Catalog #AAA5754332) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "K 01-162, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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