JAM2 recombinant protein
Recombinant Human JAM2 Protein
Gene Names
JAM2; JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43
Reactivity
Human
Applications
ELISA, Western Blot, SDS-Page
Purity
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Synonyms
JAM2; Recombinant Human JAM2 Protein; C21orf43; VEJAM; Junctional adhesion molecule B; JAM-B; Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD322; JAM2 recombinant protein
Host
Human cells
Reactivity
Human
Purity/Purification
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Sequence
FSAPKDQQVV TAVEYQEAIL ACKTPKKTVS SRLEWKKLGR SVSFVYYQQT LQGDFKNRAE MIDFNIRIKN VTRSDAGKYR CEVSAPSEQG QNLEEDTVTL EVLVAPAVPS CEVPSSALSG TVVELRCQDK EGNPAPEYTW FKDGIRLLEN PRLGSQSTNS SYTMNTKTGT LQFNTVSKLD TGEYSCEARN SVGYRRCPGK RMQVDDLNVD HHHHHH
Sequence Length
262
Applicable Applications for JAM2 recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for JAM2 recombinant protein
Recombinant Human JAM2 Protein is produced by our Mammalian expression system and the target gene encoding Phe29-Asn236 is expressed with a 6His tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,554 Da
NCBI Official Full Name
junctional adhesion molecule B isoform 2
NCBI Official Synonym Full Names
junctional adhesion molecule 2
NCBI Official Symbol
JAM2
NCBI Official Synonym Symbols
JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43
NCBI Protein Information
junctional adhesion molecule B
UniProt Protein Name
Junctional adhesion molecule B
Protein Family
UniProt Gene Name
JAM2
UniProt Synonym Gene Names
C21orf43; VEJAM; JAM-B; JAM-2; VE-JAM
UniProt Entry Name
JAM2_HUMAN
NCBI Description
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]
Uniprot Description
JAM2: May play a role in the processes of lymphocyte homing to secondary lymphoid organs. Belongs to the immunoglobulin superfamily.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 21q21.2
Cellular Component: plasma membrane
Molecular Function: protein binding
Biological Process: extracellular matrix organization and biogenesis; leukocyte migration
Research Articles on JAM2
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Product Notes
The JAM2 jam2 (Catalog #AAA8249330) is a Recombinant Protein produced from Human cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human JAM2 Protein reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JAM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS). Researchers should empirically determine the suitability of the JAM2 jam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: FSAPKDQQVV TAVEYQEAIL ACKTPKKTVS SRLEWKKLGR SVSFVYYQQT LQGDFKNRAE MIDFNIRIKN VTRSDAGKYR CEVSAPSEQG QNLEEDTVTL EVLVAPAVPS CEVPSSALSG TVVELRCQDK EGNPAPEYTW FKDGIRLLEN PRLGSQSTNS SYTMNTKTGT LQFNTVSKLD TGEYSCEARN SVGYRRCPGK RMQVDDLNVD HHHHHH. It is sometimes possible for the material contained within the vial of "JAM2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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