Rat inositol 1, 4, 5-triphosphate receptor, type 3 ELISA Kit | ITPR3 elisa kit
Rat Inositol 1, 4, 5-trisphosphate receptor type 3, ITPR3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
receptor for Inositol 1,4,5-trisphosphate (IP3); involved in second messenger signaling [RGD, Feb 2006]
Uniprot Description
IP3R3: a multi-pass endoplasmic reticulum membrane receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Expressed in intestinal crypt and villus epithelial cells. The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region. Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues. Belongs to the InsP3 receptor family.
Protein type: Membrane protein, multi-pass; Channel, ligand-gated; Channel, calcium; Membrane protein, integral
Cellular Component: nuclear outer membrane; endoplasmic reticulum membrane; endoplasmic reticulum; integral to plasma membrane; dendrite; integral to membrane; nuclear envelope; nucleoplasm; cell soma; membrane; apical part of cell; perinuclear region of cytoplasm; cytoplasm; plasma membrane; nucleolus; nucleus; brush border; receptor complex; myelin sheath
Molecular Function: inositol 1,3,4,5 tetrakisphosphate binding; calcium ion transmembrane transporter activity; inositol hexakisphosphate binding; calcium ion binding; intracellular ligand-gated calcium channel activity; phosphoinositide binding; inositol 1,4,5-triphosphate-sensitive calcium-release channel activity
Biological Process: G-protein coupled receptor protein signaling pathway; sensory perception of umami taste; elevation of cytosolic calcium ion concentration; inositol phosphate-mediated signaling; sensory perception of sweet taste; protein heterooligomerization; calcium ion transport; sensory perception of bitter taste; response to calcium ion; protein homooligomerization; memory
Research Articles on ITPR3
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Product Notes
The Rat ITPR3 itpr3 (Catalog #AAA9331515) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331515 ELISA Kit recognizes Rat ITPR3. It is sometimes possible for the material contained within the vial of "inositol 1, 4, 5-triphosphate receptor, type 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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