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Inter-alpha-trypsin inhibitor heavy chain H5 Recombinant Protein | ITIH5 recombinant protein

Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H5

Gene Names
ITIH5; ITI-HC5; PP14776
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Inter-alpha-trypsin inhibitor heavy chain H5; Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H5; ITIH5 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Sequence Positions
Full Length of VIT Domaini, 35-161aa
Tag Info
His-SUMO-tag
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for ITIH5 recombinant protein
May act as a tumor suppressor.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30.6kD
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H5 isoform 3
NCBI Official Synonym Full Names
inter-alpha-trypsin inhibitor heavy chain family member 5
NCBI Official Symbol
ITIH5
NCBI Official Synonym Symbols
ITI-HC5; PP14776
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H5
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H5
UniProt Gene Name
ITIH5
UniProt Synonym Gene Names
KIAA1953; ITI heavy chain H5; ITI-HC5; Inter-alpha-inhibitor heavy chain 5

NCBI Description

This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Uniprot Description

ITIH5: May act as a tumor suppressor. Belongs to the ITIH family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10p14

Research Articles on ITIH5

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Product Notes

The ITIH5 itih5 (Catalog #AAA9421236) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length of VIT Domaini, 35-161aa. The Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H5 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Inter-alpha-trypsin inhibitor heavy chain H5, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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