Integrin Alpha FG GAP Repeat Containing Protein 1 (ITFG1) Recombinant Protein | ITFG1 recombinant protein

Recombinant Integrin Alpha FG GAP Repeat Containing Protein 1 (ITFG1)

Cat. Num. AAA2018519

• Gene Names: ITFG1; TIP; CDA08
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Integrin Alpha FG GAP Repeat Containing Protein 1 (ITFG1); Recombinant Integrin Alpha FG GAP Repeat Containing Protein 1 (ITFG1); ITFG1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- DLNSDK QTDLFVLRER NDLIVFLADQ NAPYFKPKVK VSFKNHSALI TSVVPGDYDG DSQMDVLLTY LPKNYAKSEL GAVIFWGQNQ TLDPNNMTIL NRTFQDEPLI MDFNGDLIPD IFGITNESNQ PQILLGGNLS WHPALTTTSK MRIPHSHAFI DLTEDFTADL FLTTLNATTS TFQFEIWENL DGNFSVSTIL EKPQNMMVVG QSAFADFDGD GHMDHLLPGC EDKNCQKSTI YLVRSGMKQW VPVLQD
• Sequence Length: 612

• Applicable Applications for ITFG1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Asp55~Asp306 (Accession # Q8TB96) with two N-terminal Tags, His-tag and T7-tag
• Subcellular Location: Membrane; Single-pass type I membrane protein. Secreted
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 5.2
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 21361933
• NCBI GeneID: 81533
• NCBI Accession #: NP_110417.2
• NCBI GenBank Nucleotide #: NM_030790.3
• UniProt Accession #: Q8TB96; Q96SR4; Q9BRE2; Q9H2V9
• Molecular Weight: 31.9kDa
• NCBI Official Full Name: T-cell immunomodulatory protein
• NCBI Official Synonym Full Names: integrin alpha FG-GAP repeat containing 1
• NCBI Official Symbol: ITFG1
• NCBI Official Synonym Symbols: TIP; CDA08
• NCBI Protein Information: T-cell immunomodulatory protein; 2310047C21Rik; T cell immunomodulatory protein; integrin-alpha FG-GAP repeat-containing protein 1
• UniProt Protein Name: T-cell immunomodulatory protein
• Protein Family: T-cell immunomodulatory protein
• UniProt Gene Name: ITFG1
• UniProt Synonym Gene Names: TIP; Protein TIP
• UniProt Entry Name: TIP_HUMAN

Uniprot Description

ITFG1: Modulator of T-cell function. Has a protective effect in graft versus host disease model. Belongs to the TIP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: integral to membrane