2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein (ispd) Recombinant Protein | ispd recombinant protein
Recombinant Danio rerio 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein (ispd)
NCBI and Uniprot Product Information
Uniprot Description
Cytidylyltransferase required for protein O-linked mannosylation (PubMed:22522421). Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production.
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Product Notes
The ispd ispd (Catalog #AAA1130833) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-462, Full length protein. The amino acid sequence is listed below: MGTVTIQLSC LRHIRKLCFS CPWEGRRLFK MLLQFHHETQ RPLDPGCLLP QDAERSADQP GRAVVDFPVA AVLPAGGSGE RMGLTTPKQF CSIFNRPLIS YTIQAFERLP WIVMVVVVVA KDNHDLMLNI VRKFNHTKVK VVHGGTTRHR SIYNGLQAFS DSTDSSTPKP KVVIIHDAVR PFVEEDLLLK ITLAAKEQGA SGAIRPLVST VIATTSESYL DHSLERAKYR ASEMPQGFLY DIIFQAYQRC SEFDLEFGTE CLHLALQYCG TNARLIEGPP TLWKVTYKRD LAAAEAIIKE TLSVSACIIA EAEEEAVELA KTLQKNLNMM ETDVIPCGKE SNVQYLSKTR NFIHISASAS SSLWVLEMVK CFEDIDHARL YPVVIVWVQL SMTKQSADSQ ETDEFMALAS EVKQRNVLLY GIKIDHSKEL EQWQRSLERL GQITLVLIRD RNMALTGQML HV. It is sometimes possible for the material contained within the vial of "2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein (ispd), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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