Ras GTPase-activating-like protein IQGAP2 (IQGAP2) Recombinant Protein | IQGAP2 recombinant protein

Recombinant Human Ras GTPase-activating-like protein IQGAP2 (IQGAP2) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ras GTPase-activating-like protein IQGAP2 (IQGAP2); Recombinant Human Ras GTPase-activating-like protein IQGAP2 (IQGAP2); partial; IQGAP2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1525

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for IQGAP2 recombinant protein

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.

NCBI and Uniprot Product Information

• NCBI GI #: 550544224
• NCBI GeneID: 10788
• NCBI Accession #: NP_001272389.1
• NCBI GenBank Nucleotide #: NM_001285460.1
• UniProt Accession #: Q13576; A8K4V1; B7Z8A4; J3KR91
• Molecular Weight: 122,806 Da
• NCBI Official Full Name: ras GTPase-activating-like protein IQGAP2 isoform 2
• NCBI Official Synonym Full Names: IQ motif containing GTPase activating protein 2
• NCBI Official Symbol: IQGAP2
• NCBI Protein Information: ras GTPase-activating-like protein IQGAP2
• UniProt Protein Name: Ras GTPase-activating-like protein IQGAP2
• Protein Family: Ras GTPase-activating-like protein
• UniProt Gene Name: IQGAP2

NCBI Description

This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

Uniprot Description

Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.