Human IQ motif containing GTPase activating protein 2 ELISA Kit | IQGAP2 elisa kit

Human Ras GTPase-activating-like protein IQGAP2, IQGAP2 ELISA Kit

Cat. Num. AAA9340077

• Reactivity: Human
• Synonyms: IQ motif containing GTPase activating protein 2; Human Ras GTPase-activating-like protein IQGAP2; IQGAP2 ELISA Kit; Human Ras GTPase-activating-like protein IQGAP2 (IQGAP2) ELISA kit; IQGAP2 elisa kit

• Reactivity: Human

• Samples: Human Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) are less than 15%
• Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for IQGAP2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of IPPK (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 550544224
• NCBI GeneID: 10788
• NCBI Accession #: NP_001272389.1
• NCBI GenBank Nucleotide #: NM_001285460.1
• UniProt Accession #: Q13576; A8K4V1; B7Z8A4; J3KR91
• Molecular Weight: 180,578 Da
• NCBI Official Full Name: ras GTPase-activating-like protein IQGAP2 isoform 2
• NCBI Official Synonym Full Names: IQ motif containing GTPase activating protein 2
• NCBI Official Symbol: IQGAP2
• NCBI Protein Information: ras GTPase-activating-like protein IQGAP2
• UniProt Protein Name: Ras GTPase-activating-like protein IQGAP2
• Protein Family: Ras GTPase-activating-like protein
• UniProt Gene Name: IQGAP2
• UniProt Entry Name: IQGA2_HUMAN

NCBI Description

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]

Uniprot Description

IQGAP2: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. Isoform 2 expression is enhanced in testis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; G protein regulator, misc.

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: filamentous actin; microtubule; cell surface; microvillus; lamellipodium; cytoplasm; actin cytoskeleton; filopodium

Molecular Function: calmodulin binding; actin filament binding; Rho GTPase binding; phosphatidylinositol-3,4,5-triphosphate binding; Rac GTPase binding; actin binding; GTPase inhibitor activity

Biological Process: small GTPase mediated signal transduction; negative regulation of catalytic activity; signal transduction