SDS-Page
TLR4/CD284 Active Protein | TLR4 active protein
TLR4/CD284, Human Recombinant
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Purity
>95% by SDS-PAGE
Synonyms
TLR4/CD284; Human Recombinant; ARMD10; CD284; TLR-4; TLR4; TOLL; TLR4 active protein
Host
Insect cells (sf9)
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid. Sterile Filtered colorless solution
Sequence Positions
aa24-631
Gene Source
Human
Solubility
In 20 mM Tris
500 mM NaCl
pH 7.4 and 10% glycerol
500 mM NaCl
pH 7.4 and 10% glycerol
Biological Activity
Measured by its binding ability in a functional ELISA. The concentration of human recombinant MD2 that produces 50% optimal binding response with immobilized human recombinant TLR4 at 2 ug/mL (100 uL/well) is approximately 0.5 ug/mL.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Testing Data
Testing Data
Related Product Information for TLR4 active protein
TLR4 is a member of Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR4 receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. TLR family member which plays a fundamental role in pathogen recognition and activation of innate immunity
Product Categories/Family for TLR4 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
95,680 Da
NCBI Official Full Name
toll-like receptor 4 isoform C
NCBI Official Synonym Full Names
toll-like receptor 4
NCBI Official Symbol
TLR4
NCBI Official Synonym Symbols
TOLL; CD284; TLR-4; ARMD10
NCBI Protein Information
toll-like receptor 4; hToll; homolog of Drosophila toll
UniProt Protein Name
Toll-like receptor 4
Protein Family
UniProt Gene Name
TLR4
UniProt Entry Name
TLR4_HUMAN
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Product Notes
The TLR4 tlr4 (Catalog #AAA8400041) is an Active Protein produced from Insect cells (sf9) and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is aa24-631. It is sometimes possible for the material contained within the vial of "TLR4/CD284, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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