Miropin (Tannerella forsythia serine protease inhibitor) Protein | BFO_3114 protein
Miropin (Tannerella forsythia serine protease inhibitor)
Purity
>95% by SDS-PAGE analysis
Synonyms
Miropin (Tannerella forsythia serine protease inhibitor); BFO_3114 protein
Host
Insect cell culture
Purity/Purification
>95% by SDS-PAGE analysis
Form/Format
Frozen liquid. PBS
Concentration
0.5mg/ml (varies by lot)
Extintion Coefficient
0.945
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -70 degree C
Expiration: 3 years from delivery
Shipping: Dry Ice
Expiration: 3 years from delivery
Shipping: Dry Ice
Related Product Information for BFO_3114 protein
Miropin is a prokaryotic serpin (SErine Protease INhibitor) protein from Tannerella forsythia, a human pathogen involved in the pathogenesis of periodontitis. Miropin can inhibit the activity of a broad range of proteases including trypsin, cathepsin G, neutrophil and pancreatic elastases. Therefore, miropin is a unique serpin in its wide range of inhibitory activity. Recombinantly produced in insect cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at the N terminus for purification. This recombinant miropin inhibits the activity of human neutrophil elastase in vitro. At least 95 percent pure as determined by SDS-PAGE.
References
1. Ksiazek, M., Mizgalska, D., Enghild, J.J., Scavenius, C.,Thogersen, I.B., and Potempa, J. Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop. (2015) J. Biol. Chem. 290: 658-670.
NCBI and Uniprot Product Information
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Product Notes
The BFO_3114 (Catalog #AAA136141) is a Protein produced from Insect cell culture and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Miropin (Tannerella forsythia serine protease inhibitor), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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