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Type I Inositol 1, 4, 5-Trisphosphate 5-Phosphatase/INPP5A Recombinant Protein | INPP5A recombinant protein

Recombinant Human Type I Inositol 1, 4, 5-Trisphosphate 5-Phosphatase/INPP5A Protein (C-6His)

Gene Names
INPP5A; 5PTASE
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Type I Inositol 1; 4; 5-Trisphosphate 5-Phosphatase/INPP5A; Recombinant Human Type I Inositol 1; 5-Trisphosphate 5-Phosphatase/INPP5A Protein (C-6His); Type I inositol 1; 5-trisphosphate 5-phosphatase; INPP5A; INPP5A recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence Positions
Met1-Val410
Sequence Length
348
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for INPP5A recombinant protein
Type I inositol 1, 4, 5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1, 4, 5-trisphosphate 5-phosphatase type I family. Type I inositol-1, 4, 5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 48.5 kDa
Actual Protein Molecular Mass: 45 kDa
NCBI Official Full Name
type I inositol 1,4,5-trisphosphate 5-phosphatase isoform b
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase A
NCBI Official Symbol
INPP5A
NCBI Official Synonym Symbols
5PTASE
NCBI Protein Information
type I inositol 1,4,5-trisphosphate 5-phosphatase
UniProt Protein Name
Type I inositol 1,4,5-trisphosphate 5-phosphatase
UniProt Gene Name
INPP5A
UniProt Synonym Gene Names
5PTase

NCBI Description

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]

Uniprot Description

Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.

Research Articles on INPP5A

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Product Notes

The INPP5A inpp5a (Catalog #AAA2553336) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Val410. It is sometimes possible for the material contained within the vial of "Type I Inositol 1, 4, 5-Trisphosphate 5-Phosphatase/INPP5A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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