Structure
XY1, inhibitor
XY1
Purity
98.00%
Synonyms
XY1; inhibitor
Purity/Purification
98.00%
Form/Format
Powder
Formula
C17H19N3O2
CAS
1624117-53-8
Smiles
O=C(NCC(=O)N1CCCC1)Nc1ccc2ccccc2c1
Receptor (IC50)
PRMT3
Solubility
DMSO: 67.5mg/mL (227.01mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Structure
Structure
Related Product Information for XY1, inhibitor
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31nM), It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action.
Product Categories/Family for XY1, inhibitor
References
1. Børsting C, Tomas C, Morling N.SNP typing of the reference materials SRM 2391b 1-10, K562, XY1, XX74, and 007 with the SNPforID multiplex[J].Forensic Sci Int Genet. 2011 Jun;5 (3):e81-2.
2. Kaniskan, H. ümit, Szewczyk M M, Yu Z, et al. A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase3 (PRMT3)[J]. Angewandte Chemie, 2015, 127 (17):5255-5259.
3. Sontakke SD1, Kandukuri LR,uMapathy G,et al.The 34,XY1,der (13) chromosome constitution with loss of Y2 is associated with unilateral testicular hypoplasia in the endangered Indian blackbuck antelope (Antilope cervicapra).Sex Dev. 2012;6 (5):240-6.
2. Kaniskan, H. ümit, Szewczyk M M, Yu Z, et al. A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase3 (PRMT3)[J]. Angewandte Chemie, 2015, 127 (17):5255-5259.
3. Sontakke SD1, Kandukuri LR,uMapathy G,et al.The 34,XY1,der (13) chromosome constitution with loss of Y2 is associated with unilateral testicular hypoplasia in the endangered Indian blackbuck antelope (Antilope cervicapra).Sex Dev. 2012;6 (5):240-6.
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Product Notes
The XY1 (Catalog #AAA5752369) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "XY1, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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