Chemical Structure
Tiaramide hydrochloride, Inhibitor
Tiaramide hydrochloride
Purity
0.9862
Synonyms
Tiaramide hydrochloride; NTA-194; FK1160; FK 1160; FK-1160; tiaramide; inhibitor
Purity/Purification
0.9862
Form/Format
Solid
Solubility
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
OCCN(CC1)CCN1C(CN(c(cc(cc1)Cl)c1S1)C1=O)=O.Cl
Formula
C15H19Cl2N3O3S
In vitro
tiaramide inhibits platelet PLA2 through mechanisms other than the blockade of Ca-influx and intracellular Ca mobilization or antagonism to calmodulin[1].
CAS Number
35941-71-0
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for Tiaramide hydrochloride, inhibitor
Tiaramide hydrochloride is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties.
Product Categories/Family for Tiaramide hydrochloride, inhibitor
References
Takano S. Inhibition of phospholipase A2 by tiaramide in rabbit platelets. Jpn J Pharmacol. 1985 Nov;39(3):307-16. PubMed PMID: 3005729.
Iwasaki K, Noguchi H, Kamataki T, Kato R. Metabolism of tiaramide in vitro. I. Oxidative metabolism of tiaramide by human and rat liver microsomes. Xenobiotica. 1982 Apr;12(4):221-6. PubMed PMID: 7113258.
Takano S, Sakurai K, Suzuki T. Inhibitory effect of tiaramide of aggregation in vivo and on electrophoresis of rabbit platelets. Jpn J Pharmacol. 1980 Dec;30(6):905-12. PubMed PMID: 6264190.
Harvey JE, Jones P, Tanser AR. A trial of tiaramide in asthma. Allergy. 1985 Apr;40(3):198-201. PubMed PMID: 3887976.
Iwasaki K, Noguchi H, Kamataki T, Kato R. Metabolism of tiaramide in vitro. I. Oxidative metabolism of tiaramide by human and rat liver microsomes. Xenobiotica. 1982 Apr;12(4):221-6. PubMed PMID: 7113258.
Takano S, Sakurai K, Suzuki T. Inhibitory effect of tiaramide of aggregation in vivo and on electrophoresis of rabbit platelets. Jpn J Pharmacol. 1980 Dec;30(6):905-12. PubMed PMID: 6264190.
Harvey JE, Jones P, Tanser AR. A trial of tiaramide in asthma. Allergy. 1985 Apr;40(3):198-201. PubMed PMID: 3887976.
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Product Notes
The Tiaramide hydrochloride (Catalog #AAA5764870) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tiaramide hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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