Telaprevir (VX-950), Inhibitor

Telaprevir (VX-950)

Cat. Num. AAA386392

• Purity: >98%
• Synonyms: Telaprevir (VX-950); VX950; Incivek; Incivo; inhibitor

• Purity/Purification: >98%
• Form/Format: Powder
• Concentration: 0.1 mM: 14.71 mL (1 mg); 73.54 mL (5 mg); 147.08mL (10 mg); 0.5 mM: 2.94 mL (1 mg); 14.71 mL (5 mg); 29.42 mL (10 mg); 1 mM: 1.47 mL (1 mg); 7.35 mL (5 mg); 14.71 mL (10 mg); 5 mM: 0.29 mL (1 mg); 1.47 mL (5 mg); 2.94 mL (10 mg) (varies by lot)

• CAS Number: 402957-28-2
• Formula: C36H53N7O6
• SMILES: CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
• Actions: Inhibitor
• In Vivo Solvent: 30% PEG400/0.5% Tween80/5% propylene glycol
• Solubility (DMSO): 136 mg/mL (200.04 mM)
• Solubility (Ethanol): <1 mg/mL (<1 mM)
• Solubility (in vivo): 30 mg/mL
• Solubility (Water): <1 mg/mL (<1 mM)
• Availability: We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
• Preparation and Storage: at -20 degree C 3 years Powder

Chemical Structure

Related Product Information for Telaprevir (VX-950), inhibitor

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

References

Jacobs CL, .et al. StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins, Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496
Apriyanto DR, .et al. Anti-Hepatitis C Virus Activity of a Crude Extract from Longan (Dimocarpus longan Lour.) Leaves, Jpn J Infect Dis, 2016, May 20;69(3):213-20 PMID: 26255732
Mizuki Yamamoto, .et al. Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay, Antimicrob Agents Chemother, 2016, Nov; 60(11): 6532-6539 PMID: 27550352