Chemical Structure
Syk Inhibitor II, Inhibitor
Syk Inhibitor II
Purity
98.0%
Synonyms
Syk Inhibitor II; Syk inhibitor; inhibitor
Purity/Purification
98.0%
Form/Format
POWDER
CAS Number
726695-51-8
Formula
C14H15F3N6O
Smiles
NCCNC1=NC(NC2=CC(C(F)(F)F)=CC=C2)=C(C(N)=O)C=N1
Solubility
Water: 25 mg/mL; DMSO: 100 mg/mL
Pathways
Angiogenesis
Receptor
Syk
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
In Solvent: 2 years -80 degree C
Chemical Structure
Chemical Structure
Related Product Information for Syk Inhibitor II, inhibitor
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
References
1. Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.Bioorg Med Chem. 2005 Aug 15; 13(16):4936-51.
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Product Notes
The Syk Inhibitor II (Catalog #AAA5750483) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Syk Inhibitor II, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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