Resazurin sodium salt, Inhibitor

Resazurin sodium salt

Cat. Num. AAA5758542

• Purity: 96.16%
• Synonyms: Resazurin sodium salt; Diazoresorcinol (sodium); inhibitor

• Purity/Purification: 96.16%
• Form/Format: Solid. Powder

• Solubility: DMSO: 150mg/mL (597.21mM); (<1mg/ml refers to the product slightly soluble or insoluble)
• Formula: C12H6NNaO4
• SMILES: O=c1ccc2[n+]([O-])c3ccc([O-])cc3oc-2c1.[Na+]
• CAS Number: 62758-13-8
• Target & IC50: Bacterial
• Cell Research: Overnight broth cultures were used to inoculate FB containing resazurin sodium salt, resorufin sodium salt, resorufin acetate [Marker Gene Technologies, Eugene, OR; dissolved in dimethyl sulfoxide (DMSO)], resorufin butyrate or resorufin pentyl ether. In select experiments, FB was also supplemented with 3 g/dL bovine serum albumin (BSA). Immediately following inoculation and 24 hours later, cultures were serially diluted and were plated onto chocolate II agar. Plates were incubated at 37 degree C in 5% CO2 and individual colonies were enumerated. The limit of detection was 100 CFU/mL[1].
• In Vitro: Resazurin inhibits the growth of a broad range of N. gonorrhoeae isolates, including those resistant to multiple antibiotics[1]
• Preparation and Storage: Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent

Structure

Related Product Information for Resazurin sodium salt, inhibitor

Resazurin sodium salt is a blue non-fluorescent dye,is widely used as a metabolic indicator for living cells

Product Categories/Family for Resazurin sodium salt, inhibitor

Microbiology/Virology; Antibacterial

References

Schmitt D M, Connolly K L, Jerse A E, et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo[J]. International Journal of Antimicrobial Agents, 2016:S0924857916301650.
Schmitt D M, Connolly K L, Jerse A E, et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo[J]. International Journal of Antimicrobial Agents, 2016:S0924857916301650.
Schmitt D M, O'Dee D M, Cowan B N, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis[J]. Frontiers in Cellular and Infection Microbiology, 2013, 3.
Schmitt D M, O'Dee D M, Cowan B N, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis[J]. Frontiers in Cellular and Infection Microbiology, 2013, 3.