Structure
Remdesivir, Inhibitor
Remdesivir
Purity
97.62%
Synonyms
Remdesivir; GS-5734; inhibitor
Purity/Purification
97.62%
Form/Format
Solid. Powder
Solubility
DMSO: 125mg/mL (207.44mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C27H35N6O8P
SMILES
CCC(CC)COC(=O)C(C)NP(=O)(OCC1OC(C#N)(c2ccc3c(N)ncnn23)C(O)C1O)Oc1ccccc1
CAS Number
1809249-37-3
Target & IC50
SARS-CoV: ic50 74nM (EC50)
MERS-CoV: ic50 74nM (EC50)
MHV
MERS-CoV: ic50 74nM (EC50)
MHV
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Remdesivir, inhibitor
Remdesivir is a nucleoside analogue, with effective antiviral activity(EC50s of 74nM for SARS-CoV and MERS-CoV in HAE cells)
Product Categories/Family for Remdesivir, inhibitor
References
Andrea J Pruijssers, et al. Nucleoside analogues for the treatment,of coronavirus infections[J]. Curr Opin Virol. 2019 Apr;35:57-62.
Agostini M L, Andres E L, Sims A C, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease[J]. Mbio, 2018, 9(2):e00221-18.
Agostini M L, Andres E L, Sims A C, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease[J]. Mbio, 2018, 9(2):e00221-18.
Momattin H, et al. A Systematic Review of therapeutic agents for the treatment,of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)[J]. Travel Med Infect Dis. 2019 Jul - Aug;30:9-18.
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. cell research.
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. cell research.
Agostini M L, Andres E L, Sims A C, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease[J]. Mbio, 2018, 9(2):e00221-18.
Agostini M L, Andres E L, Sims A C, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease[J]. Mbio, 2018, 9(2):e00221-18.
Momattin H, et al. A Systematic Review of therapeutic agents for the treatment,of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)[J]. Travel Med Infect Dis. 2019 Jul - Aug;30:9-18.
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. cell research.
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. cell research.
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Product Notes
The Remdesivir (Catalog #AAA5758633) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Remdesivir, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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