Structure

Plerixafor octahydrochloride, Inhibitor

Plerixafor octahydrochloride

Purity

>98% (HPLC)

Synonyms

Plerixafor octahydrochloride; AMD-3100 octahydrochloride; JM-3100 octahydrochloride; SID-791 octahydrochloride; inhibitor

Ordering
Cat. Num. AAA3602205 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Purity/Purification

>98% (HPLC)

Suitability

H2O: >=42mg/mL

Target

Chemokine Receptor

Receptor

CXCL12; CXCR4

Chemical Name

1, 4, 8, 11-Tetraazacyclotetradecane, 1, 1'-[1, 4-phenylenebis(methylene)]bis-, hydrochloride(1:8)

SMILES

C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl

Molecular Formula

C28H62Cl8N8

CAS Number

155148-31-5

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Related Product Information for Plerixafor octahydrochloride, inhibitor

Plerixaforoctahydrochloride (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7. Multiple Sclerosis Preclinical

Product Categories/Family for Plerixafor octahydrochloride, inhibitor

Multiple Sclerosis; GPCR/G Protein; Inflammation/Immunology

References

1. Zabel BA, et al. J Immunol. 2009, 183 (5), 3204-3211.
2. De Clercq E, et al. Antimicrob Agents Chemother. 1994 Apr; 38 (4):668-74.
3. Pitchford SC, et al. Cell Stem Cell. 2009 Jan 9; 4 (1):62-72.

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Product Notes

The Plerixafor octahydrochloride (Catalog #AAA3602205) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Plerixafor octahydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Plerixafor octahydrochloride, Inhibitor