Structure
Phenserine, Inhibitor
Phenserine
Purity
98.00%
Synonyms
Phenserine; (-)-Eseroline phenylcarbamate; (-)-Phenserine; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C20H23N3O2
SMILES
CN1[C@](N(C)CC2)([H])[C@]2(C)C3=C1C=CC(OC(NC4=CC=CC=C4)=O)=C3
CAS Number
101246-66-6
Target & IC50
AChE
In Vitro
cholinergic function has been impaired in a spatial memory task,Phenserine treatment,improves learning [3].
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Phenserine, inhibitor
Phenserine is a derivative of Physostigmine and is annoncompetitive, long-acting and selective inhibitor of AChE.
Product Categories/Family for Phenserine, inhibitor
References
Klein J. Phenserine. Expert Opin Investig Drugs. 2007 Jul;16(7):1087-97.
Klein J. Phenserine. Expert Opin Investig Drugs. 2007 Jul;16(7):1087-97.
Asuni AA, et al. Modulation of amyloid precursor protein expression reduces beta-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75(5):684-99.
Asuni AA, et al. Modulation of amyloid precursor protein expression reduces beta-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75(5):684-99.
Janas AM, et al. The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci. 2005 Jan 21;76(10):1073-81.
Janas AM, et al. The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci. 2005 Jan 21;76(10):1073-81.
Klein J. Phenserine. Expert Opin Investig Drugs. 2007 Jul;16(7):1087-97.
Asuni AA, et al. Modulation of amyloid precursor protein expression reduces beta-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75(5):684-99.
Asuni AA, et al. Modulation of amyloid precursor protein expression reduces beta-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75(5):684-99.
Janas AM, et al. The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci. 2005 Jan 21;76(10):1073-81.
Janas AM, et al. The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci. 2005 Jan 21;76(10):1073-81.
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Product Notes
The Phenserine (Catalog #AAA5753685) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Phenserine, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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